Located about 100 metres from the grand Catholic church "Trapani Cathedral", Le Isole Hotel Trapani is nearly a 5-minute walk from the Port of Trapani. Public parking is available nearby.

You'll need 24-minute drive to Vincenzo Florio airport. When staying at the guest house, guests will be right around the corner from the Salus. The Cathedral of San Lorenzo is also located just 150 m from the Le Isole Trapani. San Vito lo Capo Shuttle bus stop is approximately a 10-minute walk away.

The rooms at the hotel include air conditioning, as well as media facilities like a flat-screen TV with satellite channels. The bathrooms come with a separate toilet and a shower, along with hair dryers and towels.

The property is in close proximity to Pizzeria Amici Miei serving Mediterranean dishes.