Situated around 15 minutes' walk from the Orto Botanico, the 4-star B&B Opera Dei Pupi Palermo features a barber shop. The bed & breakfast provides guests with Wi-Fi in public areas.

The regional contemporary art Museum Palazzo Riso is located within a few blocks of this Palermo hotel, and such natural sites as the Foro Italico is merely 1.4 km away. The grand square "Piazza Pretoria" is 500 metres from the B&B Opera Dei Pupi Palermo, while Roma - Vucciria bus stop is a mere 5 minutes' walk away. The 12th-century palace "Castello della Zisa" can also be found 2.4 km from the accommodation. The hotel is in the vicinity of Palermo Central train station.

The rooms comprise a dressing room and a mini-kitchen complete with an air conditioner, as well as free Wi-Fi and a flat-screen TV with satellite channels. Bedrooms come with extra-long beds or couch beds. A bidet, a separate toilet, and a shower, along with hairdryers and towels, are provided.

B&B Opera Dei Pupi features a free daily breakfast for guests. Antica Focacceria San Francesco is located next to this accommodation and serves Sicilian dishes, 400 metres away.