Offering a luggage room, Serafino B&B Palermo lies in La Kalsa, which is a great choice for travellers interested in architecture, history and monuments, merely 0.6 km from the Antonio Salinas Regional Archeological Museum and around 10 minutes' walk from the Piazza Marina. This Palermo hotel features Wi-Fi, provided in the rooms.

Fontana Pretoria Fountain is only an 8-minute walk away, while Palermo Central train station is in proximity to the bed & breakfast. Historical sights here include the 12th-century palace "Castello della Zisa", which stands 2.5 km from the Serafino B&B Palermo. Guests might as well enjoy proximity to Villa Giulia, situated about a 5-minute drive away. The property is also not far from the Cuba Palace and Via Paolo Balsamo bus station is a mere 0.8 km away.

Serafino B&B features 10 rooms with a mini-kitchen, furnished with a writing table. There is also a private bathroom.

The hotel offers an Italian breakfast made fresh daily. This accommodation is within 5 minutes' walk of Antica Focacceria San Francesco and offers a broad selection of meals.