Built in 1800, the smoke-free Nh Collection Palermo Palazzo Sitano Hotel is located approximately a 5-minute walk from Chiesa di San Domenico Baroque Church in La Kalsa, which is a great choice for travellers interested in architecture, history and monuments. Boasting access to the architecturally diverse church "Cattedrale di Palermo", merely 1 km away, this 4-star hotel includes a sauna and a shared lounge providing guests with air-conditioned rooms.

The hotel is in the vicinity of the Baroque Quattro Canti Square and Palazzo Conte Federico is a mere 14 minutes' walk away. Cuba Palace is in close proximity to the Nh Collection Palermo, while Vittorio Emanuele Fontana di Garaffo bus stop is just 50 metres away. Also, Villetta di Piazza Florio is situated about a 15-minute stroll away. The nearby shopping sights include the grand square "Piazza Pretoria", which is 500 metres away. Palermo Central train station can be found within 15 minutes' walk of the Nh Collection.

The rooms comprise a balcony and a sitting area complete with air conditioning, as well as a TV set. The private bathrooms offer a bidet, a separate toilet, and shower/tub combinations. The property offers rooms with views of the city.

Nh Collection Palermo Palazzo Sitano Hotel serves varied buffet breakfast in the morning. This Palermo hotel has the à la carte restaurant where guests can sample examples of Italian cuisine. The lounge bar will set you up nicely for enjoying your stay. Antica Focacceria San Francesco has its own variety of Sicilian meals and is approximately 200 metres away.