Offering a restaurant and a shopping area, the 4-star smoke-free Nh Collection Palermo Palazzo Sitano Hotel lies in La Kalsa, which is a great choice for travellers interested in architecture, history and monuments, a mere 1.1 km from the Palazzo Conte Federico and a mere 14 minutes' walk from such cultural places of interest as Teatro Massimo. Located in the vicinity of the architecturally diverse church "Cattedrale di Palermo", the elegant hotel features 80 rooms with views of the city.

This historical-style hotel is notable for its perfect location 550 metres from the Baroque Quattro Canti Square and a mere 1.1 km from Palermo Central train station. The Cuba Palace is approximately 25 minutes' walk away, while the Church of San Francesco of Assisi is right around the corner from the Nh Collection Palermo Palazzo Sitano. Guests might as well visit Villetta di Piazza Florio, which is merely 1.2 km away. Standing 600 metres away, the 17th-century Chiesa di San Giuseppe dei Teatini is a hard-to-miss divine tourist destination. Situated in the historical centre of Palermo, Nh Collection Palermo Palazzo Sitano Hotel is just around the corner from Vittorio Emanuele Fontana di Garaffo bus stop.

The soundproof rooms are equipped with a safe, free Wi-Fi and a satellite flat-screen TV, along with a mini-fridge-bar, tea and coffee-making facilities. There is also a private bathroom. Spacious bathrooms feature a bidet, a separate toilet, and a shower/bath combination, as well as such comforts as bathrobes and towels.

Each morning, the Nh Collection Palermo Palazzo Sitano serves a varied buffet breakfast. A lounge bar is available on site. Enjoy Sicilian cuisine in the restaurant Antica Focacceria San Francesco, situated nearly a 5-minute ride away.