Located nearly a 25-minute walk from the 12th-century palace "Castello della Zisa", Mazzini Studios Palermo hotel is only 500 m from the grandiose 19th-century theatre "Politeama Garibaldi Theater". The guest house provides a safety deposit box to ensure guests' safety.

This Palermo hotel is about 25 km from Falcone-Borsellino airport and in proximity to such cultural venues as Teatro Massimo. The Piazza Marina also lies within 30 minutes' walk of the Mazzini Studios Palermo. Giardino Inglese Garden is a short way from the property. This hotel is 300 metres from Piazza Don Sturzo bus station, while the medieval Church of San Giovanni degli Eremiti is about 2 km away.

Located just moments from the accommodation, the seafood restaurant Mazzini 30 Taverna offers a contemporary menu.