Offering air-conditioned rooms and Wi-Fi throughout the property, the 4-star Locanda Santamarina Dimora Di Charme Palermo is just 0.7 km from the regional contemporary art Museum Palazzo Riso and 19 minutes' walk from the Gemmellaro Geological Museum. Situated just around the corner from Teatro Massimo, the hotel features an à la carte restaurant serving Italian cuisine.

The comfortable hotel in the Monte di Pieta district enjoys the proximity of tourist attractions such as the 17th-century Oratory of the Rosary of St. Cita Chapel, which stands 6 minutes' walk away. Places of worship to visit 950 metres from the Locanda Santamarina Dimora Di Charme include the architecturally diverse church "Cattedrale di Palermo". This property is also within reach of the food markets of Palermo. Roma - Poste bus stop is within 10 minutes' walk of the hotel and within 15 minutes' walk of is enough to get to Palermo Central train station.

The rooms at the Locanda Santamarina Dimora Di Charme Palermo provide guests with a flat-screen TV with satellite channels, as well as comforts such as climate control. There are spacious bedrooms and family bathrooms with a bidet, a separate toilet, and a shower provided. Bathrooms with a bidet, a separate toilet, and a shower, also include a hairdryer and bath sheets. The rooms at Locanda Santamarina Dimora Di Charme offer views of the city.

Terrazze Santamarina, an onsite restaurant, is open for dinner. There is a restaurant serving Sicilian food 450 metres away.