Situated fairly close to the smoke-free La Casa Di Aneupe Hotel Syracuse, guests can reach the Catacombs of St. Lucia in no time. The 4-star hotel features safety facilities including luggage storage.

The guest house is about 5 minutes' walk from the Catholic church "Santuario della Madonna delle Lacrime" and the Piazza del Duomo is just 1.5 km away. The Greek Theatre is approximately 25 minutes on foot from the La Casa Di Aneupe Syracuse, while Fontanarossa airport is 65 km from it. The Syracuse Cathedral is just 1.6 km away, while Siracusa train station is situated a short way from the property. You can catch the bus at Arsenale sud bus stop, within 5 minutes' walk of this Syracuse hotel.

The rooms at La Casa Di Aneupe Hotel include an iron and ironing board, and climate control, as well as media facilities like a flat-screen TV with satellite channels. They are appointed with a writing desk, and also feature a mini-fridge-bar. A bidet, a separate toilet, and a shower, along with a hairdryer and bath sheets, are featured.

Trattoria da Gianni is 400 metres away and serves Southern-Italian cuisine.