Located 3.4 km from the natural Fountain of Arethusa, the comfortable Il Casale Residence Plemmirio hotel offers air-conditioned rooms about 10 minutes by car from the Piazza del Duomo. The 4-star aparthotel boasts views of the garden and offers Wi-Fi throughout the property.

This Plemmirio hotel has a convenient location within a 6-km distance of the performing arts theater "Teatro Greco", while shopping venues like the Old Market of Ortigia are 4.2 km away. History lovers will enjoy visiting the late 14th-century palace "Palazzo Montalto" (3.8 km) and the baroque palace "Palazzo Beneventano Del Bosco" (3.7 km). Located around a 15-minute drive from the Il Casale Residence Plemmirio, the Historic catholic Cathedral of Syracuse is open for visiting by worshippers and tourists. Isola bus stop is also in proximity to the property.

The air-conditioned rooms include a patio and a terrace, as well as bathrooms with a bidet, a separate toilet, and a shower, and such comforts as shower caps and bath sheets. If you like cooking, there is a fridge and kitchenware provided on site. A bidet, a separate toilet, and a shower, along with a shower cap and bath sheets, are provided.

The seafood restaurant Ostrica Park is located merely 1.1 km from Il Casale Residence hotel.