Located only 1.6 km from the 14th-century Oratory of the Rosary of St. Cita Church, Home Casa Professa 2 Palermo hotel is only a 5-minute walk from the Church of Saint Catherine of Alexandria. Guests who stay at this hotel can park their car nearby.

The hotel lies just 1.1 km from Giardino di Palazzo Jung and just a few steps from the monumental Fontana Pretoria Fountain. The Oratory of Saint Lawrence is within 10 minutes' walk of the Home Casa Professa 2, while Maqueda - Palazzo Comitini bus stop is approximately 200 metres away. This property is located 2.2 km from the 12th-century palace "Castello della Zisa". For those travelling from afar, Falcone-Borsellino airport is 30 minutes' drive away.

An iron with ironing board and air conditioning, along with tea and coffee making facilities, provide in-room convenience at the Home Casa Professa 2 Palermo. Bathrooms inlude a bidet, a separate toilet, and a shower, and such fine comforts as a hair dryer and bath sheets.

Ferro di Cavallo offers a selection of dishes a 7-minute walk away.