Located around 25 minutes' walk from Teatro Massimo, the recently renovated Guastella House Hotel Palermo is 450 m from the Ajutamicristo Palace. Guests who stay at this 3-star guest house can park their car nearby.

The hotel is about 35 km from Falcone-Borsellino airport and within reach of such cultural venues as the Sant'Anna Modern Art Gallery. The Museum of Tiles Stanze al Genio is in the immediate vicinity of the Guastella House Palermo, while Dei Mille - Balsamo bus stop is a mere 100 metres away. The nearby attractions include the Orto Botanico, situated just a 9-minute walk away.

The rooms feature climate control, along with a flat-screen TV with satellite channels for guests' utmost comfort. Offering a separate toilet and a shower, the bathrooms are also appointed with a hair dryer and towels.

Pasticceria Vabres is located next to Guastella House Hotel and serves Italian dishes, 250 metres from the property.