Featuring Wi-Fi throughout the property, Hotel Florio Palermo sits a 25-minute walk from the Palermo Cathedral. This hotel in a historical district has 2 outdoor swimming pools, as well as a private parking lot on site.

The Monument to the Fallen in the Fight Against the Mafia is located right near the 2-star hotel, and Falcone-Borsellino airport is approximately a 27-minute drive away. The Florio in Palermo is 2.2 km from the Diocesan Museum of Palermo. This property also takes you to the 12th-century palace "Castello della Zisa", which is a 30-minute walk away. A local bus stop Isidoro Carini is about 400 metres away.

The hotel features a buffet breakfast daily. Guests may find the seafood restaurant Trattoria Piccolo Napoli a 5-minute stroll away.