Duca Di Villena Palermo hotel offers its guests bright rooms 700 metres from the Baroque Quattro Canti Square. Private car parking is available for EUR 15 per day nearby.

Martorana co-Cathedral is located within a few blocks of the guest house, and the ancient Palatine Chapel is a 17-minute walk away. The Duca Di Villena Palermo is situated 0.7 km from the 17th-century Chiesa di San Giuseppe dei Teatini, which is considered to be a sacred site. The medieval Church of San Giovanni degli Eremiti can also be found in proximity to this 4-star hotel. The property is just a 5-minute walk from Roma - Vucciria bus station.

This hotel offers 6 rooms with a minibar fridge, coffee and tea making facilities, and such modern conveniences as a flat-screen TV with satellite channels. The private bathrooms come with a bidet, a separate toilet, and a shower.

Duca Di Villena hotel is just around the corner from the restaurant Antica Focacceria San Francesco.