The comfortable 3-star Hotel D'Orleans Palermo includes air-conditioned rooms only 1.5 km from the Baroque Quattro Canti Square. There is a train station near the smoke-free hotel, and guests can easily reach the medieval Church of San Giovanni degli Eremiti which is just 600 metres away.

The Gemmellaro Geological Museum is located merely 0.8 km away, and the ancient Palatine Chapel is within a few blocks of this Palermo hotel. The D'Orleans Palermo offers proximity to such natural sights as the Foro Italico (2.1 km) and the animal park "Parco D'orleans" (1 km). Guests might as well visit Piazza Indipendenza, which is nearly a 10-minute walk away. The nearby notable religious buildings include the 17th-century Church of the Gesu, just 1.2 km from the accommodation.

Offering a flat-screen TV with satellite channels, the 9 rooms come with an air conditioner to ensure a comfortable stay. There is also a family bathroom. A bidet, a separate toilet, and a shower, along with hair dryers and bath sheets, are included in the bathrooms. Guests can enjoy views of the garden.

In the immediate vicinity of Hotel D'Orleans, Da Vituccio serves Italian meals.