Situated nearly a 25-minute walk from the 17th-century Church of the Gesu and 600 m from the Waldensian Evangelical Church, the smoke-free Donnafrancaflorio Hotel Palermo features a banquet hall for various purposes. This 4-star guest house provides guests with Wi-Fi in public areas.

Palermo, Borgo Vecchio district is located right near the hotel, and Falcone-Borsellino airport is approximately a 27-minute drive away. A mere 1.9 km from the Donnafrancaflorio Palermo you will reach Martorana co-Cathedral. This accommodation is within 5 minutes' walk of Isidoro Carini bus stop and 2.5 km from Palermo Central train station in Palermo.

The hotel offers rooms with a balcony and a dining area featuring climate control, along with a flat-screen TV with satellite channels and streaming services. They are appointed with a writing desk, and also feature a mini-fridge-bar, coffee and tea makers. Bathrooms are equipped with a bidet, a separate toilet, and a shower, as well as comforts such as a hairdryer and bath sheets.

A free breakfast is served daily at the Donnafrancaflorio. Bar Lucy features Italian dishes and is situated approximately 200 metres away.