The 3-star Domenico Florio Palace Catania hotel provides proximity to the Palazzo Biscari, which is located 3.9 km away. Wi-Fi is available in public areas and public parking is provided nearby too.

The centre of Catania can be reached in 5 minutes' walk of this bed & breakfast, and such cultural venues as the sculpture museum "Museo Diocesano Catania" are about 10 minutes' drive away. The Domenico Florio Palace is 0.8 km from Via Etnea Shopping Street and only 650 metres from the Piazza Carlo Alberto market. The Palazzo degli Elefanti is around 15 minutes away by car, and Stesicoro underground station is a stone's throw from this Catania hotel. The property is located 5 km from Fontanarossa airport and near Etnea-Minoriti bus stop.

Domenico Florio Palace hotel has 6 rooms with a balcony. A flat-screen TV with satellite channels along with a mini fridge bar are provided. An air conditioner are featured for guests' comfort. Bathrooms with a bidet, a separate toilet, and a shower, also include hairdryers and bath sheets.

This hotel serves a continental breakfast in the morning. The restaurant Fud Bottega sicula is in proximity to the accommodation.