Located approximately a 20-minute walk from Orto Botanico dell'Universita di Catania, the 3-star Domenico Florio Palace Catania hotel provides guests with tour/ticket assistance for a better travel experience. Wi-Fi is available in public areas and public parking is provided nearby too.

Situated 1.3 km from the 13th-century castle "Castello Ursino", the bed & breakfast also gives access to such sports venues as Stadio Angelo Massimino Stadium, which is 2.4 km away. The Domenico Florio Palace is about 10 minutes by car from the sculpture museum "Museo Diocesano Catania" and within a few blocks of Piazza Carlo Alberto market. The nearby notable religious buildings include the Church of San Benedetto, 1.4 km from this Catania hotel. The property is located close to Stesicoro underground station and a 10-minute drive will be enough to get to Fontanarossa airport.

Domenico Florio Palace hotel has 6 rooms with a balcony. A flat-screen TV with satellite channels along with a mini fridge bar are provided. Bathrooms, equipped with a bidet, a separate toilet, and a shower, also feature hairdryers and bath sheets.

This hotel serves a continental breakfast in the morning. Situated only 550 m from the Domenico Florio Palace Catania, the bar Pasticceria Savia offers a Mediterranean menu.