Located just 1.4 km from the 12th-century Church of San Cataldo, the 4-star Difronte Palatina Chapel Hotel Palermo offers access to tourist attractions throughout Palermo. There is a shopping area available on the premises.

The centre of Palermo can be reached in 15 minutes' walk of the guest house, and such cultural venues as the Sant'Anna Modern Art Gallery are nearly a 20-minute walk away. The Church of San Giuseppe dei Teatini is just 1.3 km from the Difronte Palatina Chapel Palermo, which is also situated in close proximity to D'Orleans Park. The location will allow you to be within 25 minutes' walk of the Orto Botanico. This Palermo hotel stands close to the monumental Porta Nuova City Gate, fairly close to Indipendenza - Pisani bus stop.

The rooms comprise a terrace and a dining area complete with an air conditioner, as well as a flat-screen TV with satellite channels. Furnished with a writing desk, they also have sound-proofed windows. Bathrooms have a bidet, a separate toilet, and a shower, along with hairdryers and bath sheets.

Difronte Palatina Chapel Hotel offers a daily Italian breakfast. You can get a gastronomic experience at Trattoria Familiare da Michele & Jolanda which offers Mediterranean cuisine just a few steps from the accommodation.