Featuring Wi-Fi throughout the property, Cosmopolitan Palermo Hotel is about a 25-minute walk from the 12th-century palace "Castello della Zisa". The guest house also provides guests with a safe deposit box and luggage storage.

Teatro Massimo is a mere 0.7 km away, while Palermo Central train station is in proximity to this 4-star hotel. The Cosmopolitan gives access to the Foro Italico, which is a 17-minute walk away. Also, Giardino di Palazzo Jung is situated around 800 metres away. The Cuba Palace lies 2.1 km from the property. This accommodation is located 35 km from Falcone-Borsellino airport and within reach of Roma - Lattarini bus stop.

The rooms comprise a balcony complete with an air conditioner, as well as a flat-screen TV with satellite channels. Furnished with a writing desk, they also have sound-proof windows. Bathroom essentials include a bidet, a separate toilet, and a shower, and such comforts as hair dryers and free toiletries. Guests can take advantage of views of the city.

Only 250 metres from Cosmopolitan Palermo Hotel, Antica Focacceria San Francesco serves Southern-Italian dishes.