Located 950 m from the cathedral church "Cattedrale di Palermo", the 3-star Palermo Centro Zoe Hotel offers air-conditioned rooms merely 13 minutes' walk from the 12th-century palace "Castello della Zisa". The bed & breakfast also includes a car park.

This Palermo hotel lies 1.1 km from Garden Piersanti Mattarella and within reach of Teatro Massimo. The Centro Zoe Palermo is a mere 650 metres from Alberto Amedeo - Tribunale bus stop and nearly 5 minutes on foot from the history museum "Museo Falcone". The 17th-century Chiesa di San Giuseppe dei Teatini is in proximity to the accommodation. The hotel is a mere 1.8 km from Palermo Central train station.

The 6 rooms at the property comprise a mini-kitchen. Bathrooms are appointed with a bidet, a shower, and a shared toilet along with hair dryers and towels.

Palermo Centro Zoe Hotel features a daily continental breakfast. The seafood restaurant Torquemada is located within a few blocks of this hotel.