Casa Salice Hotel Sant'Alessio Siculo provides proximity to the Church of the Most Holy Trinity, which is situated about 3 km away. Guests who stay at the hotel can park their car on site.

The centre of Sant'Alessio Siculo can be reached in 10 minutes' walk of this guest house, and such cultural venues as the Salvatore Quasimodo Literary Park are nearly 15 minutes away by car. The Savoca stream is 4.7 km from the Casa Salice, while Fontanarossa airport is 65 km from it. There is CioccolArt Sicily Museum around a 25-minute walk from the property.

This hotel offers rooms with a balcony featuring an air conditioner, along with a flat-screen TV with satellite channels. Guests can also make use of a bidet and a shower, as well as comforts such as hair dryers and towels.

New Kursaal is adjacent to Casa Salice Hotel, 350 metres away.