The 3-star Casa Per Ferie Don Orione Palermo Hotel has 19 rooms and is located around a 10-minute walk from Teatro Franco Zappala. To keep fit, a sports hall provided for guests at the hotel.

Situated 2.9 km from the Antonio Pasqualino International Puppet Museum, this Palermo hotel also gives access to such sports venues as Stadio Renzo Barbera Football Stadium, which is 2.5 km away. Modern Art Regional Gallery Sant'Anna is in proximity to the Casa Per Ferie Don Orione, while Ammiraglio Rizzo - Piazza Acquasanta bus stop is nearly a 10-minute walk away. The property stands 3.2 km from the architecturally diverse church "Cattedrale di Palermo", popular with pilgrims and tourists alike. Falcone-Borsellino airport is 30 km from this hotel and Palermo Central train station is 3.7 km away.

The rooms at Casa Per Ferie Don Orione Palermo Hotel feature a writing desk, along with sound-proof windows for guests' convenience. A flat-screen TV with satellite channels, as well as comforts as climate control are also featured. Offering a bidet, a raised toilet, and a shower, the bathrooms are fitted with hair dryers and bath sheets.

A buffet breakfast, with different food options, is offered each morning. Guests may find the street food restaurant Panineria da Homer just a few steps from the Casa Per Ferie Don Orione Palermo.