Offering snorkeling trips, the 3-star Casa 68 Ortigia Hotel Syracuse is located around 5 minutes' walk from Teatro dei Pupi. The hotel is situated in the centre of Syracuse, 2.3 km from such cultural attractions as the Technopark Archimedes.

The Paolo Orsi Regional Archaeological Museum is a short way from this Syracuse guest house, while the 17th-century Basilica Santa Lucia al Sepolcro is 18 minutes' walk away. You can find the late 14th-century palace "Palazzo Montalto", which is a great place to explore the area, 650 m from the Casa 68 Ortigia Syracuse. Also, the accommodation is within 10 minutes' drive of the Roman Amphitheatre, and Siracusa train station is located 2.2 km away. This Syracuse hotel stands a mere 700 metres from Ortigia Island, within easy reach of Scibilia bus stop.

The rooms comprise a balcony and a kitchen complete with ironing equipment and an air conditioner, as well as a flat-screen TV with satellite channels. They are appointed with a writing table, and also feature coffee and tea making equipment. The bathroom features a separate toilet and a shower, along with bathrobes and towels.

The restaurant Irma la Dolce is located in close proximity to Casa 68 Ortigia Hotel.