Located about 25 minutes' walk from the royal Palatine Chapel, Calisa Hotel Palermo is 500 m from the unfinished Santa Maria dello Spasimo Catholic Church. Private parking is available nearby.

The guest house is not far from the Orto Botanico in La Kalsa, which is a great choice for travellers interested in architecture, history and monuments. When staying at the Calisa Palermo, guests will be a mere 1.1 km from the 17th-century Chiesa di San Giuseppe dei Teatini. Also, the hotel is in close proximity to the Church of Saint Catherine of Alexandria, and Palermo Central train station is located 400 metres away. The property is nearly 5 minutes on foot from Roma FS bus station.

This hotel offers rooms with a balcony and a seating area featuring ironing equipment, along with a multi-channel television. For your comfort, you will find a refrigerator, an oven, and kitchenware. Bathrooms include a bidet, a separate toilet, and a shower, and such comforts as hair dryers and bath sheets.

Guests may find the restaurant Antica Focacceria San Francesco a stone's throw from Calisa Hotel.