Located 3.4 km from the Valley of the Temples in Agrigento, Maredentro Bed & Breakfast San Leone is just a 5-minute walk from the night Boca Club. Guests who stay at this bed & breakfast can park their car on site.

The centre of San Leone can be reached in 10 minutes' walk of the hotel, and such cultural venues as Casa Natale di Luigi Pirandello Museum are 6 km away. Valley of the Temples National Monument in San Leone is 10 minutes' drive from the Maredentro Bed & Breakfast. Also, I Giardinetti is situated around 400 metres away. Guests of the property can get to the accessible Agrigento Regional Archaeological Museum, which is about 15 minutes away by car.

Maredentro Bed & Breakfast offers rooms with a patio and a balcony featuring an air conditioner, along with a flat-screen TV with satellite channels. They are appointed with a writing table, and also feature tea and coffee-making facilities. Bathroom comforts include a hair dryer and bath sheets, and such essentials as a bidet, a separate toilet, and a shower.

The seafood restaurant Bella Vista lies just near this property.