Providing guests with car rentals, the 4-star Domus Le Nereidi Bed & Breakfast Lampedusa is located just 1.3 km from Cala Pisana. The bed & breakfast features Wi-Fi throughout the property.

The centre of Lampedusa can be reached within a 5-minute walk, and natural attractions like Sciatu Persu Beach are approximately 25 minutes' walk away. The Portu N'Toni Beach is 2.7 km away, while the Pelagie Islands Marine Protected Area is within easy reach of the Domus Lampedusa. WWF Turtle and Wildlife Rescue Center is located 650 metres from this Lampedusa hotel. For those travelling from afar, Lampedusa airport is 5 minutes' drive away.

The property offers rooms with a seating area featuring an ironing set and an air conditioner, along with a flat-screen TV with satellite channels. They are appointed with a writing desk, and also feature a mini fridge bar and coffee/tea making machines. Bathrooms are equipped with a bidet, a roll-in shower, and a separate toilet, as well as comforts such as hair dryers and bath sheets.

Domus Le Nereidi Bed & Breakfast serves a buffet breakfast every morning and offers fresh fruits and fresh pastries. The in-house bar is ideal for a relaxing drink. The restaurant Antros AperiPUB is located a stone's throw from this hotel.