Situated about 25 minutes' walk from the Church of San Giovanni di Malta, the 4-star B&B Regina 381 Messina offers a sunbathing terrace and a picnic area.

Located approximately 2 km from the 16th - century Messina Fountain of Neptune, the hotel is also 3.9 km from Stazione Messina Centrale railway station. This Messina bed & breakfast provides history lovers with proximity to the historic Monte di Pieta Palace (2.6 km) and the Forte San Salvatore (2.2 km). There is the Galleria Vittorio Emanuele III nearly 10 minutes away by car, while Capolinea Annunziata bus station is a stone's throw from the B&B Regina 381 Messina.

The spacious rooms are fitted with an air conditioner; such modern facilities as a flat-screen TV with satellite channels and wireless internet, and include private bathrooms with a bidet, a separate toilet, and a shower. If you like cooking, there is a fridge, an oven, and kitchenware provided on site. Bathrooms offer a bidet, a separate toilet, and a shower, along with comforts such as a shower cap and bath sheets.

B&B Regina 381 features a daily gluten-free breakfast. Guests may find the restaurant Nanny Rabbit 450 metres from the property.