Situated about 25 minutes' walk from Chiesa di San Giovanni di Malta, the 4-star B&B Regina 381 Messina offers a sunbathing terrace and a picnic area.

Located approximately 2 km from the 16th-century Messina Fountain of Neptune, the hotel is also 3.9 km from Stazione Messina Centrale railway station. This Messina bed & breakfast provides history lovers with proximity to the historic Monte di Pieta Palace (2.6 km) and Forte San Salvatore (2.2 km). There is Galleria Vittorio Emanuele III nearly 10 minutes away by car, while Capolinea Annunziata bus station is fairly close to the Regina Messina.

The spacious rooms are fitted with air conditioning; such modern facilities as a flat-screen TV with satellite channels and Wi-Fi, and include private bathrooms with a bidet and a separate toilet. If you like cooking, there is a fridge, an oven, and kitchenware provided on site.

B&B Regina 381 features a daily gluten-free breakfast. Nanny Rabbit is ideal for tasting Italian cuisine and is situated a mere 450 metres from the property.