Nestled in Ortigia, which is the historical centre of Siracusa, B&B Domus Gaetani Syracuse is an 8-minute walk from the Church of St. Philip the Apostle. Featuring a luggage room, this hotel is located in the vicinity of the ancient Greek Temple of Apollo.

The 3-star bed & breakfast boasts a prime location 1.3 km from Siracusa train station. The B&B Domus Gaetani also gives access to the 17th-century Basilica Santa Lucia al Sepolcro, which is a 20-minute walk away. 2.8 km from the Paolo Orsi Regional Archaeological Museum is a perk for guests staying at this property. Archimede bus stop lies a 5-minute stroll away.

The recently renovated hotel offers rooms with a dressing area featuring air conditioning, along with a flat-screen TV with satellite channels. There is also a private bathroom. Bathrooms are fitted with a bidet, a separate toilet, and a shower as well as bathrobes and towels.

Serving Sicilian dishes, La Volpe e L'Uva lies within easy reach of B&B Domus Gaetani.