Overlooking the city, the comfortable Palazzo Monopolio Aparthotel Messina is located nearly a 10-minute walk from the Piazza European Union. This 4-star aparthotel also provides guests with a safe deposit box.

The hotel is notable for its prime location, only 0.6 km from the Bell Tower and Astronomical Clock and in the vicinity of Stazione Messina Centrale train station. The Annunziata dei Catalani Church is around 200 metres from the Palazzo Monopolio Aparthotel Messina, while Stazione Centrale bus stop is about a 10-minute walk away. This accommodation lies not far from the Temple of Christ the King.

Staying at one of the 17 rooms at the hotel, guests have access to a balcony and a dining area. There is also a private bathroom.

The seafood restaurant La Tonnara is within 5 minutes' walk of the property.