Situated just 1.6 km from the architecturally diverse church "Cattedrale di Palermo", Merlo5 Apartment Palermo also boasts easy access to Palermo Central train station which is approximately a 15-minute walk away.

Via Maqueda Street is nearly a 15-minute stroll away, while the Antonio Pasqualino International Puppet Museum is a stone's throw from the apartment. This apartment is within a 1-km distance of the 17th-century Chiesa di San Giuseppe dei Teatini in Palermo. Being in the immediate vicinity of Merlo5 Apartment, the Piazza Marina is a good place to visit.

There is Via Paolo Balsamo bus station within 10 minutes' walk of the accommodation.