Offering luggage storage, the 3-star Mariano Apartment Palermo hotel lies in the Ruggero Settimo district of Palermo, merely 1.8 km from the Foro Italico and around 25 minutes' walk from the medieval Ponte dell'Ammiraglio Bridge. Situated 35 km from Falcone-Borsellino airport, the guest house features car hire service, as well as bicycles for rent.

The hotel is in the centre of Palermo, so guests have direct access to the Baroque Quattro Canti Square, which is just a 7-minute walk away. The Mariano Palermo is 200 m from Cavour bus stop and a few steps from Chiesa di San Domenico Baroque Church. Also, the property is approximately a 5-minute ride from the Orto Botanico.

The rooms comprise a dining area complete with air conditioning, as well as a flat-screen TV with satellite channels. A fridge and kitchenware are available upon request. A bidet, a separate toilet, and a shower, along with a hairdryer and bath sheets, are featured.

The restaurant Ristorante Pizzeria Ruvolo is right around the corner from the Mariano.