Overlooking the city, Opera Prima 28 Hotel Palermo is 7 minutes' walk from Oratory of the Rosary of St. Cita. This Palermo guest house features Wi-Fi, provided throughout the property.

Located just 550 metres from the monumental Fontana Pretoria Fountain, the property is also within walking distance of entertainment venues like Politeama Garibaldi Theater. The area includes such religious sights as the Prominent baroque Church of the Gesu (1.5 km) and Palatine Chapel (1.6 km). The hotel is situated merely 1.5 km from Church of San Cataldo, while Piazza Don Sturzo bus station lies merely 10 minutes' stroll away. For those travelling from afar, Falcone-Borsellino airport is 29 minutes' drive away.

The air-conditioned rooms at the Opera Prima 28 Palermo are fitted with a flat-screen television, some of them feature a tiled floor and soundproof windows. A bidet, a separate toilet, and a shower, along with hairdryers and bath sheets, are provided.

Situated right off the property, the brew pub Bisogno Di Vino offers an Italian menu.